Plan Ledger DOL Form 5500 · updated monthly

Karyopharm Therapeutics Inc.401(k)

KARYOPHARM THERAPEUTICS INC. 401(K) PLAN · NEWTON, MA · plan year 2024

Reported admin expense ratio · 2024
0.12%

Peer grade: A- · admin costs + employer contributions vs same-size plans · how grading works

Karyopharm Therapeutics Inc. reported $62,878 in plan administrative expenses for 2024: 0.12% of average plan assets, below the peer median. Employer contributions averaged $8,848 per active participant. This ratio covers administrative expenses reported on the plan's Schedule H only; fund-level expense ratios are not included in public structured data — see methodology.

Across the 2 years on file its reported administrative ratio fell from 0.14% to 0.12%. The plan sits in the $50M–$250M size bracket, benchmarked here against 10,352 comparable plans and shown alongside other manufacturing employers. By assets it is the 652nd-largest of 2,726 plans among Massachusetts employers on file, and the 2,912th of 13,661 in manufacturing. In 2024, employees put in $2.19 for every $1.00 the employer contributed; active participation has shrunk from 401 to 284 since 2022.

Plan summary
Net assets, end of year$55,627,157
Participants with balances484
Active participants284
Employer contributions$2,512,829
Employee contributions$5,505,491
Employer contribution per active participant$8,848
Average account balance$114,932
Benefits paid to participants$7,413,977
Plan auditUnmodified (clean) audit opinion
Plan history3
Yearassets · accounts · employer contribution
2024$55.6M · 484 accts · $2.5M emplr
2023$46.1M · 523 accts · $3.2M emplr
2022$36.0M · 545 accts · $3.1M emplr
Administrative expenses, itemized · 2024
Recordkeeping & contract admin$62,878
Total administrative$62,878
The Karyopharm Therapeutics Inc. 401(k) match · 2024
Employer contribution per active participant$8,848
Median for plans this size$3,635
2024$8,848 per active participant
2023$10,434 per active participant
2022$7,683 per active participant

Karyopharm Therapeutics Inc.'s 2024 employer contribution ran above the $3,635 median for plans its size, placing it in the top quarter of its peers. Filings report dollars actually contributed, not the match formula; the formula itself (for example, 50% of the first 6% of pay) lives in the plan's summary plan description from HR.

What these fees cost you

Annual cost at the plan's reported 2024 administrative ratio, against the median plan its size; fund expense ratios are extra. Compare any plan.

Service providers · 20241
FIDELITY INVESTMENTS INSTITUTIONAL · Loan processing$62,878

Compensation shown is direct payments from plan assets reported on Schedule C. Providers paid through fund revenue-sharing appear as indirect.

Administrative cost history3
2024$62,878 · 0.12%
2023$50,144 · 0.12%
2022$53,094 · 0.14%
Same employer
Similar plansManufacturing · Massachusetts
Gn Audio USA, Inc. MA$56.9M · 0.27%
Ufp Technologies, Inc. MA$56.1M · 0.37%
Agenus Inc. MA$52.7M · 0.03%
Chase Corporation MA$52.3M · 0.25%
Harvard Bioscience, Inc. MA$49.7M · 0.07%

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Source: U.S. Department of Labor, Form 5500 series, EIN 263931704 · Verify on EFAST2 · Amounts are as reported by the plan sponsor for the plan year shown.